To treat Patellofemoral Syndrome with physical therapy, focus on exercises that strengthen the quadriceps, hamstrings, and hip muscles to improve knee alignment and stability. Stretching the hamstrings and calves helps reduce tension around the knee. Low-impact activities like cycling or swimming can maintain fitness without overloading the joint. Taping or bracing may provide temporary support. Gradually progress to more functional movements while avoiding activities that cause pain, ensuring proper mechanics and alignment throughout exercises.